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Vioxx: What To Know
Contact your doctor immediately if you experience swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness; flu-like symptoms; sluggishness; yellowing of the skin or eyes; stomach pain; dark urine or pale stools; or unusual fatigue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Vioxx: What Is It
Vioxx (Rofecoxib) is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and to treat pain and menstrual discomfort.

Vioxx: Before Using
Some medicines or medical conditions may interact with Vioxx (Rofecoxib). Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking. Additional monitoring of your dose or condition may be needed if you are taking an ACE inhibitor, an anticoagulant, furosemide, lithium, methotrexate, rifampin, thiazide diuretics, or warfarin.

Vioxx: How To Use
The usual dose of Vioxx (Rofecoxib) for treatment of osteoarthritis is 12.5 mg daily although some patients may benefit from 25 mg daily. The maximum daily Vioxx (Rofecoxib) dose should not exceed 25 mg.

Vioxx: Storage
Store Vioxx (Rofecoxib) at room temperature at 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light.

Vioxx: Missed Dose
If you miss a dose of Vioxx (Rofecoxib) and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed Vioxx (Rofecoxib) dose if you do not remember until the next day. Do not take 2 Vioxx (Rofecoxib) doses at once.

Vioxx: Side Effects
Side effects that may occur while taking Vioxx (Rofecoxib) include weakness or nausea. If they continue or are bothersome, check with your doctor. Check with your doctor as soon as possible if you experience itching or skin rash, swelling of the feet or ankles, unexpected weight gain, vomiting material that looks like coffee grounds, or blood in stool or vomit.

Vioxx: Precautions
Do not take Vioxx (Rofecoxib) if you have had a severe allergic reaction to aspirin or any medicine containing aspirin or to a nonsteroidal anti-inflammatory drug (such as Feldene, Motrin, Naprosyn, Clinoril). A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. 

Vioxx: Notes
Do not share Vioxx (Rofecoxib) with others for whom it was not prescribed. Do not use Vioxx (Rofecoxib) for other health conditions. Keep Vioxx (Rofecoxib) out of the reach of children. if using Vioxx (Rofecoxib) for an extended period of time, obtain refills before your supply runs out.

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